Sentence examples for difficulty in crossing from inspiring English sources

They had intended to head north by bus or train and were surprised to hear they may now face difficulty in crossing the border.

However, hydrophilic photosensitizers poorly accumulate in tumor cells as it finds difficulty in crossing cell membranes.

One possible explanation for the virulence defect is that ssn8 mutant cells may have difficulty in crossing the blood brain barrier due to their elongated cell morphology, or may be defective in putative brain predilection factor(s), which is yet to be demonstrated.

Chemotherapy is also with limited effects, since most chemicals have difficulty in crossing the blood brain barrier [ 4].

PRMT5 inhibitors also halted growth of glioblastoma tumors implanted under the skin of mice, but they did not work as well in tumors located in the brain, because of the difficulties in crossing the blood-brain barrier.

According to this, John, a wealthy and powerful "priest and king," reputedly a lineal descendant of the Magi who had visited the Christ Child, defeated the Muslim kings of Persia in battle, stormed their capital at Ecbatana, and intended to proceed to Jerusalem but was impeded in the last goal because of difficulties in crossing the Tigris River.

He added that the increase of army checkpoints around Devecik made people uneasy: "If they want peace, they should decrease the symbols of war". According to sources quoting local PKK commanders, withdrawing rebel groups face some difficulties in crossing the Turkish-Iraqi border due to heightened security measures.

Here, we acknowledge the challenges that face the world as a whole, including the difficulties in sharing information freely, the difficulties in crossing cultural and language barriers, and the difficulties in maintaining sensitivity to the concerns of each nation.

In SOT, He-ALA peaks are delayed as compared to ALA lotion, and this can be explained either by considering the additional step of esterase breakage of the alcohol chain, difficulties in crossing the stratum corneum.

The international community is now pushing on an open door in Myanmar; the real difficulty is in crossing the threshold effectively to achieve an agreed-upon objective.

The difficulty and anxiety in crossing the border, the armed surveillance everywhere, the Unknown on the other side, only a block away, intimidating and almost scary with its different atmosphere and politics.