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One major difficulty in conducting the study was uptake of 'opt in' consent, reflected by only 53% of adolescent and young adult patients being contactable.
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We don't have parallel research showing the same thing in humans (at least not yet) because of ethical and legal difficulties in conducting the research, but the animal findings suggest that marijuana is more of a sexual inhibitor than it is a sexual enhancer.
Because of logistic difficulties in conducting the study in the canopy, we could not differentiate between bird and bat predation in the canopy; it was impossible to remove and re-install the nets on a daily basis as carried out in the study of Kalka et al. [8] in the understorey and in the study of Williams-Guillén et al. [10] in agricultural areas.
Both of these factors increased the practical difficulties in conducting the study.
Analysis of this qualitative data has highlighted that difficulties in conducting the trial stemmed not just from the challenges associated with the complexity of the intervention but also from the complexity of the local organisational culture.
Given the difficulty in conducting this type of research, it is not surprising that this remains a considerable – but important – gap in the literature.
One major difficulty in conducting this review and meta-analysis was the wide range of different outcome measures used and the ways in which such measures were analyzed and presented.
Contamination between treatment arms has also been reported: increased PL EPA with placebo and no increase in PL EPA with supplementation (Fearon et al, 2003, 2006), demonstrating the difficulties in conducting these studies, as patients who understand the potential benefits of EPA may be driven to take EPA supplementation on their own initiative.
Taken together, the existing literature reflects the difficulty in conducting and analyzing studies of the potential benefits of tracheostomy in patients with acute respiratory failure.
(Wc.10) They told us rudely about the difficulty in conducting normal delivery -if you want the mother and baby, agree to the surgery or take them somewhere else.
The small number of studies identified as part of this review may, to some degree, be an artefact of the difficulty in conducting a review of economic evaluations in the areas of health promotion and public health.
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