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The underlying reason for this is the difficulty in characterizing exposure and the lack of toxicity studies essential for human health risk assessment (HHRA).
As this expanded Incremental model is predominantly based on the same data as was used in the estimation of Vm, the source of variability is easily attributed to the difficulty in characterizing the proximal deposits with one measurement.
The nature of the denatured state ensemble has been controversial for decades owing, in large part, to the difficulty in characterizing the structure and energetics of denatured state interactions.
The difficulty in characterizing this process lies in its template-independent nature in the Golgi apparatus.
Despite the inherent difficulty in characterizing historic diets in evolutionary studies, there is evidence supporting recent and continuous diet-driven selection in humans (58).
If this degree of difficulty in characterizing longer-term exposure in pregnancy is true in general of BPA, epidemiologists face a challenge in finding true associations between developmental exposure with outcomes, should any exist.
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The proposed approach overcomes difficulties in characterizing RAS design and operation.
At times, traffic analysts face difficulties in characterizing and modeling such congested flow of traffic, thereby, addressing this issue effectively.
Reichenbach accepts this weakening to avoid some of the difficulties in characterizing a random sequence, and to broaden his earlier notions of probability to include sequences of trials, which might not be perfectly independent.
Several recent technological breakthroughs have eliminated two fundamental difficulties in characterizing the relationship between pre-AUG AN and translation efficiency in S. cerevisiae.
These are principally due to the not fully known nanomaterial hazardous properties, as well as to the difficulties in characterizing exposure and defining emerging risks for the workforce.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com