Sentence examples for difficulty in activating from inspiring English sources
Taking advantage of these advances, in 1993 Eshhar et al. pioneered to design a gene composed of a single chain variable fragment (scFv) of an antibody linked with ζ chains, which is aimed to overcome the difficulty in activating anti-tumor T cells through the TCR (Eshhar et al., 1993).
However, an important drawback of these described methods is the difficulty in activating the right process at the right location in the right cells at the right time for a sufficient amount of time, while minimizing adverse reactions [ 87].
These manipulations can inform us on whether performance deficits are associated with an inability to inhibit the previous task set (i.e. overriding the previously relevant S-R rule), or with difficulty in activating the upcoming task set (i.e. rule retrieval).
Difficulties in activating the non-invasive ventilation mode were frequent with Servo-U, V500 and V680.
Moreover, despite numerous efforts, we encountered technical difficulties in activating DISOPRED for offline large-scale analysis.
Once initial difficulties in activating concepts from inputs have been overcome, the semantic access impairments that occur in both semantic aphasia and Wernicke's aphasia are best explained in terms of damage to this modulatory system in prefrontal cortex, as opposed to abnormalities within the representational system per se.
The higher recruitment threshold of these fibres is suggested to result in a greater difficulty in fully activating this muscle group.
AT&T's number, which works out to about 81 activations a minute, could also reflect the difficulty many iPhone customers had in activating their phones during the first few days, rather than disappointing sales, some analysts said.
The moderate yields of 21 from epoxide 17 and diol 18, coupled with the difficulties in selectively activating the secondary alcohol of 18, led us to investigate cyclic systems.
Due to the difficulty in systematically categorizing activating mutants in PMD, our analysis focused instead on the SWISS-PROT mutants.
These properties are consistent with the difficulty of activating CRISPR spacer uptake in the laboratory, but appear to conflict with the high complexity and diversity of the CRISPR immune systems that are found among the Sulfolobales.
