In view of the difficulties for applying the common-used microarray analysis methods such as t-test, SAM, and FDR for small sample size experiment, Chen and his colleagues [ 2] proposed a model-based information sharing method (MBIS) that enhances the power of statistical test by utilizing information shared among genes.
In practice, the difficulty of applying for patents for designs and utility models is relatively low.
A good deal of criticism has been aimed at TTM, regarding, for example, the difficulty of applying the model to complex dietary behavior [ 3, 6– 11].
Mr. Johnson alluded to the difficulty of applying the Clean Air Act, designed for conventional pollutants like sulfur dioxide and nitrogen oxide, to greenhouse gases.
The boundary conditions used to represent macroscopic-gradient-related effects in arbitrary geometries with the lattice Boltzmann methods need a trade-off between the complexity of the scheme, due to the loss of localness and the difficulties for directly applying link-based approaches, and the accuracy obtained.
Finally, we present practical guidelines for applying this strategy considering several scenarios of increasing difficulty.
One of the primary reasons for difficulty in applying known theory is the capricious variability of natural soil in contrast to the idealized soils required to develop a theory.
There are several reasons for this, including the difficulty in applying concepts developed for one kingdom of life to another, but in recent years the importance of horizontal gene transfer or recombination has also become a point of contention.
Documentary research occupied the greatest proportion of his time, because he experienced difficulty in applying the techniques for developing a documentary research strategy taught during the training.
Although he has skills in basic engineering, Carlos said, he has difficulty applying for jobs because he does not have a Social Security number and cannot get a driver's license.
