The strategies (a e) were matched to specific stages of change, based on perceived difficulty derived from our formative research: Pre-contemplation stage: only general strategies.
We evaluate three metrics as predictors of relative model detection difficulty derived from previous works: (1) Penetrance table variance (PTV), (2) customized odds ratio (COR), and (3) our own Ease of Detection Measure (EDM), calculated from the penetrance values and respective genotype frequencies of each simulated genetic model.
To overcome potential difficulties deriving from the syncytium organization of Tuber hyphae, which upon transformation become a mosaic with only one transformed nucleus surrounded by a multitude of untransformed nuclei, we used TAIL-PCR as a sensitive tool to recover flanking-DNA sequences (Liu and Whittier [1995]).
To a lesser extent, quality of care is measured in developing countries also, but when it comes to humanitarian aid settings, difficulties deriving from disaster settings seem to hinder effective evaluations of quality of care (1).
Toklas's financial difficulties derived from Gertrude Stein's will.
Ironically, part of Orwell's difficulties derived from the success of Animal Farm.
A large part of AIG's difficulties derive from a London office that dealt in complex transactions providing insurance on securities once considered low-risk, such as mortgage-related assets at the height of the property boom.
The difficulties have been grouped in accordance with origin: (a) difficulties derived from the context of the intervention; (b) the characteristics of the offender; (c) the therapist.
There are also certain difficulties derived from the lack of standardisation in the evaluation of β-catenin expression and the heterogeneity that most colorectal cancers have with respect to the distribution of nuclear β-catenin expression [ 21].
It is proposed that many of these difficulties derive from an adherence to a traditional medical model of disease and that the application of a biopsychosocial approach would be more effective for both research and individual case management.
