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No Lisch nodules or oculomotor difficulties were detected.
Additional counseling was provided if adherence difficulties were detected.
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One limitation of the HeRQoLED-S is that its items did not cover the entire range of existing difficulties, and gaps in construct difficulty were detected.
Major neurological symptoms, such as sensory/motor deficit, deterioration of mental status, gait disturbance, or swallowing difficulty, were detected in 53 patients (36.1%).
Several SNP associations for direct calving difficulty were detected for each of the three breeds, although the exact location and direction of the effects of these associations differed between breeds.
For the drug assessment, the biggest differences in proportion of students with difficulty were detected for variable property of experimental subject and measurement of outcome, and it was less sensitive for detecting difference in difficulties for manipulation of variables (medium-gray bars in Figure 2, C and D).
The same genomic region on chromosome 13 (around 56.55 Mb) that was significantly associated with maternal calving difficulty was detected with both association approaches (Bonferroni corrected p = 2.53 × 10−5; q = 2.53 × 10−6; BF = 220.36); however, no candidate gene was identified in this region.
Interventions (more teaching, one-on-one tutoring) should begin as early as the difficulty is detected.
In practice, the difficulty is detecting the target early enough that the intercept point is still within range of the missile.
The difficulty to detect balancing selection is further illustrated by the low concordance between the 5 previous studies aiming at detecting balancing selection, where only 1.3% of all identified candidate regions were detected in more than one study.
In the third step, the invariance of item difficulty hierarchy was detected across diagnostic groups through DIF tests.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com