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Such research would encounter difficulties to prove public value in early stages of research and would therefore hardly be funded under a strict PE regime.
A further explanation for the difficulties to prove the two-hit model relates to the nature of the CCM tissue.
The major difficulties to prove the hypotheses of symptom specifity i.e. that the sensory modality of the defective monitoring mechanism determines the sensory modality of resulting psychotic symptoms depends on certain assumptions included in experimental designs: The first premise is to address both the function of the action monitoring system and passivity symptoms directly.
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However, the independence of these constraints results in a poor lower bounding, hence a difficulty to prove optimality.
"There is no more difficulty to prove there are no weapons of mass destruction than to prove there's no rhinoceros in my sitting room".
Using Lemmas 2.2, 2.3 and the L 1 − L ∞ estimate of the linear wave equation with zero initial data, it is not difficulty to prove the following.
The biggest barrier or difficulty to prove the positivity of (82) is mainly how to deal with the squared term in (82).
For the case (n>1), the difficulty to prove the global existence of solutions may be that the free boundaries can intersect with each other.
Since S is an unbounded domain, the difficulty to prove Theorems 1 and 2 lies in the fact that (W_{0}^{1,p}(S)) cannot be compactly embedded into (L^{q}(S)) for any (qin p, p_{N,m}^)).
This change should come about because current risk assessment methodology presents too much regulatory difficulty to prove that certain effects will ultimately lead to a reduction in the population level.
When we consider nonlocal differential systems with indefinite weights, another difficulty is to prove (T: Kto K); for detail to see the proof of Lemma 2.4.
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