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Not for Jeremy Duke, 54, a creative therapist, who spends much of his life helping adults with learning difficulties to express themselves through art.
Although they had difficulties to express their needs, their disabilities were not an absolute hindrance once they had cognitive functions and skills that could be employed in some PD practices.
On the one hand, this observation might be the consequence of technical difficulties to express Plasmodium proteins in yeast and sampling issues that arise from choosing random fragments to screen.
In the literature it has been pointed out that persons with dementia might need extended time to assimilate impressions, and they often have difficulties to express their needs and verbalise ideas due to working memory impairment [ 2, 4].
For example, one non-user was dyslexic and stated that he finds it easier to speak to his GP face-to-face due to the difficulties to express himself.
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One of the major difficulties of developing serological test for the detection of M. pneumoniae is the difficulty to express its proteins in heterologous expression system as the Mycoplasmas use the UGA opal codon to incorporate tryptophan rather than as a stop codon as in the universal genetic code [ 31], leading to premature termination of the protein synthesis.
Alexithymia concerns incapacity or difficulty to express emotions through words.
The first is the difficulty to express complex outcomes through a single money measure.
One of the challenges for biochemical characterization of p300/CBP is the difficulty to express and purify active enzyme.
This situation, partly resulting from the difficulties faced to express these receptors in vitro, also reflects a more problematic situation, which is the very limited number of known potential agonists.
This problem can be simplified by using a Lagrangian formulation, in which case the only major difficulty is to express the influence of turbulence on calculated trajectories.
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