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However, teachers may have difficulties to design and deliver a pedagogically well-designed and technically smoothly executable online or blended PBL process on their own because they lack appropriate expertise in learning theories and design methods as well as a deeper understanding of the potential affordances of the available technologies.
The antigenic diversity observed in many vaccine candidates is one of the difficulties to design effective malaria vaccine.
Our former pilot studies including Miao et al. (2013, 2014, 2015) have shown that the difficulties to design and deliver a pedagogically high-quality, human-readable, reusable, sharable, and computer-executable online or blended PBL process are reduced as intended.
The analysis of those reports led to interesting results about their reflective skills and abilities as well as their difficulties to design collaboratively.
In fact, this topic has been included in Computer Science curriculum, but students present difficulties to design MPI parallel applications efficiently.
However, because of their expensive cost and for difficulties to design the gas flow field channels to machine, it should be considered to search out the alternative materials from graphite to carbon carbon composite and carbon polymer composites.
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When that's the case, co-optimization poses unique difficulties to designing and assessing algorithms.
However, evolutionary approaches have a difficulty to design the controller that conducts complex behaviors.
Since the BVI is a very complicated model, it is quite difficulty to design an algorithm that is efficient for all examples.
Autopilots for yacht are very difficulty to design due to serious nonlinear and non-minimum phase characteristics of yachts.
Such trials are in our opinion difficult to carry on, not only because of a relative difficulty to randomize patients but also because of an objective difficulty to design an appropriate study [32].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com