Recently, an article was released giving an overview of all published microarray based microgravity studies [ 57] describing the difficulties to combine and overlay the data from different experiments, study objects, microgravity platforms (simulated microgravity, sounding rocket, space shuttle, and ISS missions), and different microarray experimental designs [ 58– 64].
A limit of this last approach is the difficulty to combine the sample aberrated wavefront and the reference arm wavefront.
Computationally speaking, the difficulty is to combine high performance computing with the need to couple various codes or solvers, each representing a different scale or a different physical process.
However, there are well known difficulties about attempting to combine results from studies which are too dissimilar [ 3].
This trade-off between potential and tolerance, present even in the absence of physiologically costly avoidance, explains the difficulty to breed to combine tolerance with performance (Kumar et al. 2008; Heinemann et al. 2011; Serraj et al. 2011).
To overcome such difficulties, it is promising to combine STM-LE spectroscopy with plasmon enhancement on surfaces.
Indeed, as Augustine points out in book V of his De Trinitate, there is a special difficulty for those want to combine this conception with the Christian doctrine of creation.
Since some of the ingredients are fairly thick and sticky, you may have difficulty using a whisk to combine them.
Glimcher, for one, has little patience for handwringing about the difficulties women face in trying to combine a career in academic medicine with family life.
This was partly due to difficulties combining refurbished Nimrod MR2 fuselages, which had not been built to a common standard, with newly built wings.
However, the frequent co-occurrence of psychological aggression with physical violence, as well as difficulties in measurement, combine to reduce certainty with regard to the independent effects of psychological aggression on health.
