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We also discuss the difficulties to apply such methodologies to molecular targeted therapies development.
Alternative reasons not to use guidelines were difficulties to apply guidelines to their patient population (3%) or an unawareness of the existence of such guidelines (2%).
The analysis was performed to substantiate or refute the claims of the healthcare providers about the difficulties to apply the PAMP recommendations on young children as the reason for non-adherence.
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The tensions above filtered down to the command center -- a series of rooms on the third floor of a tower on BP's campus in Houston's Westlake section -- where the seasoned well experts faced a challenge of unparalleled scale and difficulty: to apply techniques used often on land to an out-of-control well 5,000 feet underwater.
Another reason not to use guidelines was a difficulty to apply them in daily clinical practice (4%), including a lack of resources in order to monitor (2%).
Hindering factors are the high threshold to connect with colleagues from outside the sector and the difficulty to apply the lessons learnt in the own company.
The main difficulty to apply rate-distortion optimization once the codestream is constructed is that rate-distortion statistics collected during the encoding process are no longer available.
The purpose of the article is to improve the spread foundation calculation method in respect of reduction of difficulty to apply of proposed method by developing the software.
However, for quasibrittle materials used in Civil Engineering such as concrete or wood, the difficulty to apply a pure bending moment lies inappropriated the method used for composites.
Another factor that can hinder networking for organizational innovations is the difficulty to apply the lessons learnt in the own company: "A lot of theories are used, but the practical implication is another story" (farmer interview).
As such, the bifurcation diagram shown in Fig. 1 is an indication of the difficulty to apply the theory of cortical hallucinations developed in [8] where it was assumed that such stereotyped cortical patterns could be explained by adjusting the network parameters close to bifurcations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com