Traditional hazard analysis techniques often rely upon static models of component interaction and have difficulties exploring the effects of multiple coincident failures.
Patients with cirrhosis and minimal hepatic encephalopathy (MHE) have driving difficulties but the effects of therapy on driving performance is unclear.
However, studies of this type have run into inherent difficulties because the effects of different variables on evolutionary rates are hard to tease apart.
Although there are positive aspects to guideline studies (i.e., reproducible methods), even validated laboratories have difficulties replicating the effects of specific compounds at specific doses [ 36].
Just think of the difficulties of unravelling the effects of technology and tariff cuts; then remember that trade is about a lot more than border measures.
The National Hurricane Center struggled to predict Tropical Storm Franklin mainly due to difficulties in predicting the effects of wind shear.
The difficulties in assessing the effects of exposure by timing present in carefully designed observational studies and even trial results.
Last, we recognise the methodological difficulties in distinguishing the effects of partnership processes from the effects of research in the content area.
Additionally, these authors acknowledge the difficulties in extricating the effects of childhood body size from correlated adult body size with breast cancer risk.
The lack of a true control-group in step-2 can result in difficulties to interpret the effects of the stress-intervention.
