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The idea is to test potential therapies for human diseases on nonhuman models to avoid practical and ethical difficulties that limit research on humans.
TEE has the advantage of being less invasive; however TEE-based estimation of LVEDP using correlates such as left ventricular end-diastolic volume (LVEDV) has technical difficulties that limit its clinical usefulness.
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The dearth of these advanced understandings in the previous studies is largely due to technical difficulties that limited both their scope and depth.
Moreover, for an instance class of the k-set cover problem, we disclose how SEIP, using either one-bit or bit-wise mutation, can overcome the difficulty that limits the greedy algorithm.
However, these methods for similarity calculation are only at a word or concept level rather than a semantic level, since they measure the similarity merely based on the common words or concepts in the query and sentence, which is the major difficulty that limits the performance improvement for text summarization system.
Surfactant instillation by flexible feeding tube has several technical difficulties that may limit its widespread application.
The authors also delve into the experimental and computational difficulties that currently limit the potential of such techniques.
Exclusion criteria were having had biopterin therapy within 8 weeks prior to study involvement, pregnancy or planning to become pregnant, and literacy or comprehension difficulties that would limit patient ability to provide informed consent or complete the QOL questionnaire.
Combining a recognition of the methodological difficulties that have limited electrophysiological analyses with an understanding of the structural features of the endings, however, suggests several critical electrophysiological experiments with the resolution to distinguish two classes of response profiles.
On the other hand, patients with expected airway difficulties receive SAD that limit the risk for adverse events during the induction phase of anesthesia.
6 The first goal of our study was to use DTI to assess the microstructure of white matter in schizophrenia, as far as possible overcoming the methodological difficulties that may have limited previous DTI studies of this disorder.
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CEO of Professional Science Editing for Scientists @ prosciediting.com