These differences in metabolite coverage arise because of many reasons, including separation difficulties, sensitivity differences, instrument detection differences, targeted vs. non-targeted methods, compound stability, compound solubility, compound volatility, etc.
Her sons, seven-year-old Dylan Beadle and his four-year-old brother Jake both love Christmas but their social difficulties, sensitivities about touch, taste and noise, and untypical reactions to certain situations, have led mum Tracy and dad Glen to approach this part of the year a little differently.
Further, vaccine design and diagnosis technology have met with difficulties in sensitivity, specificity and reproducibility.
In the current study, sleep fragmentation was indirectly assessed by adjusting for sleep difficulties in sensitivity analyses, whereas physical activity and prevalent diabetes/heart disease, and snoring (as a proxy for sleep apnoea) were considered as confounders and effect modifiers.
If the cells in question are neurons, he says, disrupted communication could result perhaps underlying the social difficulties; heightened sensitivity to sights, sounds, and sensations; and intolerance for anything new that often afflict patients with autism.
The concerns about floor and ceiling effects is regarding the ability to discriminate between healthier patients and patients with more severe conditions and also difficulties with sensitivity and responsiveness to changes [ 32].
Delicate Case for Prosecutors The handling of Father Díaz's case in Queens is instructive in another way, reflecting some of the difficulties and sensitivities confronted by prosecutors.
How we deal with this difficulty requires sensitivity to competing interests, now and in the future, and a full appreciation of legal, social, technical, economic, and ethical considerations.
Although fatigue is a very important property in terms of safety when designing mechanical components, it has rarely been considered in topology optimization with the lack of concept and the difficulty of sensitivity analysis for fatigue constraints calculated from multiaxial cycle counting.
The seiche of Leyte Gulf enhanced the storm surge, and it is one of difficulties and sensitivities of the hindcast of this event in addition to typhoon track hindcast.
The reluctance to address these difficulties and sensitivities, however, might be hampering patients' ability to make informed decisions about their future treatment.
