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The main difficulties remaining for prospective use of RNA-Seq in individualized breast cancer treatment are analyzing RNA-Seq data in the n-of-1 setting and the lack of an open source reporting tool providing clinically actionable information.
Briefly, the sleep diary contained questions regarding how often during the previous week HD patients experienced any of the following: (1) difficulties falling asleep, (2) number of nocturnal awakenings, (3) difficulties remaining asleep, (4) the sensation of waking-up tired and fatigued, (5) day time stress and (6) how often did they feel refreshed after the night's sleep.
Similar(58)
However, direct modeling of protein binding site flexibility remains challenging because of the large conformational space that must be sampled, and difficulties remain in constructing a suitably accurate energy function.
The difficulties remain enormous.
But difficulties remain.
And important difficulties remain.
Difficulties remain despite reorganization efforts.
Still, a few difficulties remained.
But the political difficulties remain formidable.
That is probably true, but difficulties remain.
Despite those efforts, considerable difficulties remained.
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CEO of Professional Science Editing for Scientists @ prosciediting.com