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Despite papers citing their diagnostic utility, limited clinical use of these agents may have resulted from logistical difficulties of utilizing these in everyday workflow, safety concerns, and lack of commercial success, resulting in their non-availability[ 1 3].
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All of these factors increase the complexity and difficulty of utilizing a single type of dressing.
Recognizing potential false positives from adopting the Bloom filter, consideration of reducing it per the Bloom filter's design parameters is discussed, while the difficulty of utilizing the false positives due to hashing based indexing of the Bloom filter for malicious attack is noted.
This consideration highlights the difficulty of utilizing the CSC theory to design new strategies against cancer, since it can be inferred that it will be necessary to effectively target both CSCs and non-CSCs or multiple marker populations in order to achieve true therapeutic benefits.
Other sources of variability could be related to the cut off values used for PCR detection or to the fact that only half of the patients studied had reliable information in regards to the gene expression, thus underscoring the difficulty of realistically utilizing this assay for clinical purposes.
However, users have aggravating difficulties in utilizing the potentials of desktop GeoVEs because of navigation and wayfinding constraints.
Pre- and post-tests were found to be of comparable difficulty by utilizing a separate group of reference learners, emergency medicine interns, whose mean pre-test score was 55.83% ± 15.51 and mean post-test score was 58.33% ± 11.68.
This poses difficulties in utilizing them in practical plant breeding.
In addition, IBD individuals can have difficulty in utilizing iron appropriately because it has low levels of erythropoietin for their severity of anemia [ 22].
Few studies included four-part fractures, likely reflecting the technical difficulty in utilizing IMN for this pattern, in addition to the number of alternative implants available.
This diversity causes difficulties in optimally utilizing existing resources and competencies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com