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It will be seen that the proposed procedure considerably removes the difficulties of the existing methods and provides a promising tool for material design of functionally graded structures.
The investigation also indicates that homotopy methods not only overcome the computational difficulties of the existing methods for locally reacting liners, but also give a completely different way to calculate the eigenvalues of non-locally reacting liners, which have recently received considerable attention due to their potential application for future advanced liners.
In our evaluation, we demonstrated the difficulties of the existing tools in providing full range estimates that include the proportions of all domains of life and viruses.
Our results on simulated and real data reveal the difficulties of the existing methods when measuring achaeal or viral abundances and show the overall good profiling performance of the protein-based mixture model.
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The mixture of sounds from different pitches pose difficulties for the existing techniques.
Major limitations of the study are explained through either the low quality of the reviewed studies or the difficulties of applying the existing evidence to the German health care system.
G4S and Serco were singled out for particular criticism, after struggling to get their contracts up and running because of "negotiating difficulties" with the existing housing suppliers.
There are further difficulties with the existing studies of cerebral asymmetry in SLI.
Difficulty in interpreting some of the existing research arises because of the incipient state of knowledge regarding boron nutriture, to analytical problems associated with determining accurately the small quantities of boron in feed and tissues, and to technological difficulties in controlling extraneous exposure of experimental animals to boron.
In light of the difficulties presented by the existing literature, our objective was to define a reasonable, physiologically based and clinically relevant time point at which tracheostomy should be considered in critically ill patients requiring MV.
On top of the existing difficulties, May's speech on the Downing Street steps put further pressure on her health team by stressing her determination to tackle inequalities in life expectancy and providing better life chances for those suffering from mental illness.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com