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Both studies (42, 43) have also highlighted the difficulties of scoring CNPs and CNVs, where batch effects make unbiased evaluation of associations challenging (44, 45).
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Choi, whose up-and-down round of 70 included three bogeys, one double bogey and six birdies, talked about the difficulty of scoring.
The takeaway here, aside from the difficulty of scoring high CTRs, is that 5% is neither a realistic target for many organizations nor a true measure of an ad's success.
In this area, it is very difficult to identify the ground truth," says Rhue. Imagine the difficulty of scoring for a level of happiness in the face, for example.
He also noted the increased difficulty of scoring a game for which there was no linear plotline, a major change from the previous Final Fantasy games.
And Anthem, which has been complaining (albeit quietly) about the difficulty of scoring profits in the exchange market, has been buying up Medicaid insurers — including Simply Healthcare, which had nearly 200,000 Medicaid and Medicare members in Florida, for $1 billion last year. .
Breeding for improvement of fruit flavor is a very challenging task when using classical breeding methods due to the difficulty of scoring and quantifying such a complex trait.
Equivalent figures for indels were in keeping with the increased difficulty of scoring these variants from low-pass sequencing data at 84 and 20.7%, respectively (Materials and Methods; Supplementary Material, Fig. S3 and Tables S4 7).
However, the difficulty and tedium of scoring all the chromosome fragments, as well as the inability to readily detect exchange aberrations, has limited the use of PCC.
Many worry about the practical difficulties of administering, scoring and interpreting QoL questionnaires, although some researchers have achieved this successfully in their own routine oncology practice [ 23].
His apothegms were always illuminating: "Football is a game where superiority in match play can't always be indicated by goals, because of the difficulty of scoring". He inherited a talented England team, though it must be emphasised that he never, officially, had responsibility for picking it.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com