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Implementation of the potential of mean force in the simulations of biological processes, such as enzyme catalysis, can help overcome the difficulties of sampling specific regions on the energy landscape and provide useful insights to understand the catalytic mechanism.
Which kind of blew my mind, but Qinghua Guo stepped in with some helpful words about the difficulties of sampling from a joint probability distribution in Monte Carlo simulations, etc. Plus we had some great times with Jacob, Leo, Yanjun and the Green Valley International crew who were showcasing their series of Lidar instruments and software.
Still, due to the difficulties of sampling from such a large number of often poorly known species, the assignment of some genera is still awaiting confirmation.
Challenges arise due to the difficulties of sampling from this site, and the majority of studies have been conducted utilising peripheral blood mononuclear cells.
There are few studies of biological processes during the polar night, largely owing to the logistical difficulties of sampling.
Consequently, the model constructed in the present study can be extended when studying a country's population, which would overcome the logistic difficulties of sampling high numbers of animals.
Similar(52)
Nevertheless, their measurement is not easy on account of heterogeneity in property and difficulty of sampling.
Although the molecular and functional characteristics of BAT have been intensively studied in rodents, only a few studies have used human BAT specimens due to the difficulty of sampling human BAT deposits.
The challenges come from compartmentation of metabolites, from dilution of tracer by endogenous pools, and from the difficulty of sampling relevant pools.
The patterns of soil moisture in arid environments are very important for the conservation and restoration of vegetation but have been rarely studied due to the difficulty of sampling in these environments.
We used a novel technique, based on semi-structured interviews with local informants, to address the difficulty of sampling relatively rare but important events, such as dispersal between fragments.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com