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Because of the difficulties of its measurement, it is not routinely used in clinical practice but some authors proposed to use heart lung interaction under mechanical ventilation for its estimation.
Hale's dilemma is directed primarily against fictionalists who take the literal content of their fiction to be false, and those fictionalists prepared to ascribe some other status to their fictional claims avoid the dilemma as initially stated (though this route may encounter difficulties of its own, especially if it retains some sort of conditional analysis of the "according to PW" prefix).
Using "budget reconciliation" as an end run around the filibuster is a possibility (no decision on that has yet been made), but it's rife with difficulties of its own.
The board took a close look at Mars Polar Lander to ensure that it would not encounter unexpected difficulties of its own.
The London School of Economics became embroiled in difficulties of its own with an oppressive regime when it emerged in 2011 that it had close links with the government of Muammar el-Qaddafi of Libya, including accepting training contracts worth millions and a donation from the dictator's son Seif al-Islam Qaddafi.
But it is also fraught with potential difficulties of its own.
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The mutual information criterion may be used in that context, but it suffers from the difficulty of its estimation through a finite set of samples.
The test "adapts" itself to your skill level: It will adjust the difficulty of its questions to your ability to answer earlier questions correctly.
Harvard even played down the difficulty of its entrance exam in ads, reprinted above, that it placed in The New York Times in September 1870, noting that of the 210 candidates who took its test the June before, "185 were admitted".
The Times reported the "dismay" of the panel at the difficulty of its job.
But making "Into the Abyss," Mr. Herzog said, particularly jarred him with the difficulty of its intimate, on-camera confrontations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com