Emotional difficulties, manifested in feelings of isolation and withdrawal from social interaction, were reported by participants in all four groups.
However, the combination of the online medium and the home-base also exacerbate the challenges manifested in the two types of business, for example, engendering feelings of isolation and difficulties in establishing trust (Anwar and Daniel, 2014).
Adjusting to language courses and a new university were easy enough, yet I failed to prepare myself entirely for the moments of isolation and the difficulty of immersing myself in a foreign culture and society, no matter how much I had studied it beforehand.
To overcome the difficulty of the isolation and to increase the thermodynamic and kinetic stabilities of HSB, various ideas are proposed by making efficient use of the substituent effects - theoretical molecular designing.
Importance of high mortality rate of this infections is once more increased due to scantiness of choosing antibiotics of treatment and difficulty of isolation.
Due to the scarcity of methods for the stereoselective incorporation of halides into organic substrates and the difficulty of isolation from nature, access to most members for anticancer screening is severely limited.
As most of the current prevalence data on Lyme disease are from human medical institutions and identification of Borrelia is based on the isolation, it is reasonable to believe that in northeast China, B. valaisiana is more prevalent but may be misdiagnosed due to the difficulty of isolation of the pathogen.
Study of M. genitalium genetic variation has been hampered by the limited availability of genetic materials due to difficulties in isolation and cultivation of this organism from clinical specimens.
Elucidating the physiological significance of an orphan cytochrome P450s is a complicated process hampered by difficulties in isolation and purification of CYPs as well as identifying possible substrates from a myriad of potential chemicals.
Studying macrophages in vitro raises some difficulties, because isolation and culture of macrophages from synovial tissue is disturbed by the overgrowth of fibroblasts.
