As Russell himself put it in 1909 "the difficulty of discovering the truth does not prove that there is no truth to be discovered" (Philosophical Essays: 20/Papers 6: 20/Papers
This change of strategy was provoked by the increasing complexity and difficulty of discovering and developing new drugs and by skyrocketing drug-development costs.
Plaintiffs will encounter at least three substantial deterrents: expense, time, and the difficulty of discovering substantial incriminating evidence before a complaint is even filed.
In view of the difficulty of discovering uncommon alleles, and the large effect of allele misclassification on power [7], this second benefit may often be important.
Indeed, it is the difficulty of discovering or even conceiving of mechanisms of directed adaptive change in genomes that have for decades relegated the Lamarckian scheme to trash heap of history.
It is indeed a matter of great difficulty to discover [cognoscere], and effectually to distinguish [actu discriminare], the true motions of particular bodies from the apparent; because the parts of that immovable space, in which those motions are performed, do by no means come under the observation of our senses [incurrent in sensus].
Scientists often have difficulties in discovering genetics of plasma cell neoplasms due to problem of sorting plasma cells.
In fact, previous difficulties in discovering the distinctive features of AIEC strains could occur because non-phylogenetically related AIEC and non-AIEC strains have usually been compared17,24 and most AIEC studied belonged to a particular phylogroup27,30.
