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These problems, in association with the technical difficulties of determination of thiamine blood concentration, make MR imaging of the brain the most important and effective tool in the diagnostic assessment of WE.
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Reliability of numbers very limited because of technical difficulties of accurate determination of very low CYP activities cEstimated using PROD activities.
Reliability of numbers is very limited because of technical difficulties of accurate determination of very low CYP activities dEstimated using BQOD and erythromycin N-demethylase activities.
Although the laboratory tests initially increased the difficulty of diagnosis, determination of the causative organism from blood culture finally led the diagnosis.
While both decision aids explain the difficulties of the exact determination of gestational age, and describe the risks associated with late and post term pregnancies, only the British one discloses the uncertainties around the calculation of these risks.
Despite the urgent need for detailed structural information of membrane proteins, biophysical characterization is severely limited by sample incompatibilities with analytical methods, the scarcity of nonperturbing model membrane systems, and the difficulties of crystal structure determination of protein lipid samples.
As pointed out by Wang et al. [2], there are difficulties in determination of activity coefficients of reaction species in a constant ionic medium.
Considering the difficulties of direct experimental determinations of the noise factor of matching networks with sufficient accuracy, it is helpful to estimate the noise factor by calculation.
Thus, comparisons with respect to CYPs appear only borderline possible in large part because of technical difficulties of sufficiently accurate determinations of their very low activities.
Due to the difficulties in determination of reference points for AVR measurement in A&D our own method of SRM was performed on the pre- and postcorrectional ICT scans.
Due to the difficulties regarding determination of the aromatase protein expression and activity, cyclooxygenase-2 (COX-2) has been proposed as a surrogate marker for aromatase expression [ 34].
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