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They also had a fascinating piece about the difficulties of calculating the rate.
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I will not get into the difficulty of calculating true intrinsic value, except to say that it involves "real" assets, the effect of inflation and book value.
The error would become greater if used a medoid instead of a mean due to the difficulty of calculating an absolute distance [32].
However, the health secretary said this UK-wide approach would "pass the buck to Westminster", and Alcohol Focus Scotland said it was unworkable because of the difficulty of calculating production costs.
This arises not because arrivals cannot be averaged over any given period, but because of the difficulty of calculating the exact profile of arrivals at the queue tail whose position itself affects the timing of arrivals.
Due to the difficulty of calculating the eigenvalues of Φ, we replace the non-diagonal elements in Φ with their mean value 0 and the i th diagonal element ρ i 2 σ h 2 P + 1 g i 2 P + 1 σ h 2 P + 1 ρ i 2 g i 2 P + 1 with λ P = ρ 2 σ h 2 P + 1 σ g 2 P + 1 σ h 2 P + 1 ρ 2 σ g 2 P + 1 where ρ 2 = 1 1 + σ f 2 P s.
They allow circumventing the difficulty of calculating a likelihood function inherent to the more traditional maximum-likelihood or Bayesian approaches, which make them particularly appealing in our case.
Information on oral and powder (child) formulations was not included in the analysis due to the difficulty of calculating patient-year equivalent quantities associated with variations in pediatric weight.
Although the selection and monitoring of cell division symmetries was done on agar media, owing to the difficulty of calculating growth yields on agar media the growth rate and growth yield estimations were performed in shake flask cultures in liquid media.
Our research also highlights the limitations of the HES database and difficulty of calculating the overall burden of specific cancers in England.
A major limitation of the p1-model is the difficulty of calculating the normalizing constant, κ, since it is a sum over the entire graph space.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com