Difficulties in funding, getting the aircraft from the US Navy, and delays in completing the modifications led the USAF to scrap the S-2 based SCNA in January 1968.
Lack of homeopathic expertise by researchers or difficulties in modification of homeopathic practice goals to fit conventional diagnosis-based research designs can cause confusion in the design and execution of clinical trials and in the evaluation and interpretation of results.
Networked control systems where the sensors, controller and actuators of a digital control system reside on different computer nodes linked by a network, aim to overcome the disadvantages of conventional digital control systems at the application level, such as difficulty of modification, vulnerability to electrical noise, difficulty in maintenance and upgrades.
THE increasing use of alloy steels has produced difficulties necessitating modifications in the methods used in the analysis of plain carbon steels described in the older text-books ; and in addition, considerable research has been required in order to simplify the estimation of the various additions, which now include many of the less common elements.
Health care providers were encouraged to provide feedback throughout the duration of the study to enable us identify any difficulties and modifications that needed to be made to the protocol for the full trial.
To reduce this difficulty, several modifications to classical Y-en-Roux esophagojejunostomy have been designed.
Captive bottlenose dolphins are capable of adjusting their echolocation click amplitude yet have more difficulties in precise modification of the frequency structure of their clicks (Moore and Pawloski 1990).
Despite the huge potential of mitoTALEN-mediated mtDNA editing, more user-friendly and efficient alternative methods are necessary to overcome difficulties in mtDNA modification either for correction of dysfunctional mtDNA or for producing dysfunctional mtDNA in order to create mitochondria-associated disease models.
Prevention of cognitive disorders is an urgent priority because of the difficulty of the modification of the course of age-related cognitive decline.
Besides conventional condensation polymerization technique, some other methods have been developed, such as ring-opening polymerization of cyclic esters and the free radical ring-opening polymerization of cyclic ketene acetals, in order for their synthesis to overcome the inherent disadvantages of low molecular weight, property modification, difficulty of processing, and others.
