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The most commonly reported sleep difficulties in the sample included interrupted sleep, nocturia, snoring or coughing fits, and pain.
Unfortunately, because of the difficulties in the sample isolation and preparation of cone pigments, structural studies on these pigments have lagged significantly behind those of bovine Rho.
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Overall, the level of difficulty in the sample papers was higher than in current GCSE papers.
This situation presents a difficulty in the sample loading, injection and dispensing processes.
As reported in sample size literature in cluster-randomized controlled trial we had difficulties in defining the sample size for the dual nature of the trial that focused both on individuals and clusters.
The specific difficulties in this sample can be explained, to some extent, by the greater proportion of people with motor disabilities and by the geographical and architectural barriers involved.
All participants indicated that the instructions were easy to follow and had no difficulties in collecting the sample.
However, less data are available for normal or reference values of element concentrations for CSF samples due to the difficulties in accessing the samples and low concentrations of elements.
Although the measurement of nanoscale film thermal conductivity has been made in the thickness range of about 100 nm, the direct measurement tools face problems due to the difficulties in preparing the samples and test apparatus for the thickness range of less than 100 nm.
Due to the difficulty in loading the sample in the shape of a perfect cylinder and almost certain inhomogeneity of the samples at molecular level, at least 20 replicate measurements were performed and representative results were chosen for analysis.
However, the use of buccal DNA for more demanding, large-scale genetic applications can be problematic [5], [6]: for instance, DNA that is of poor quality due to degradation can lead to incorrect or missing genotype calls, discordant results in samples subjected to whole genome amplification, and difficulties in using the samples in DNA-pooling experiments [7], [8].
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CEO of Professional Science Editing for Scientists @ prosciediting.com