Sentence examples for difficulties in systematic from inspiring English sources

Despite its advantages, P. pastoris cultivation is plagued by high protease expression levels, high sensitivity to methanol levels, nutrient-deficiency when grown on defined media, difficulties in systematic study due to product-specific effects, and health and safety concerns associated with the storage of large quantities of methanol.

There are, however, difficulties in using systematic reviews and meta-analyses of this clinical evidence to inform guidelines and clinical practice.

Nevertheless, the use of natural products in drug discovery has significantly declined in the past two decades, due in part to persisting difficulties in the systematic isolation and synthesis of such molecules [3].

There are technical difficulties in performing systematic and generalised, time-consuming analyses for sperm quality [ 6] and libido assessment using serving capacity tests (SCT) in commercial flocks [ 7].

This antithesis entails a difficulty in implementing systematic follow-up and quality work.

Research on the diagnosis of pneumonia is usually hampered by difficulties in obtaining a systematic comparison with CT scan.

Morphological convergence appears to be a common theme in coral evolution [ 35] and our analysis points out some of the difficulties in determining the systematic positions of extinct taxa.

This review epitomises the difficulties and pitfalls encountered in systematic reviews of observational studies.

The aim of this paper is to identify the difficulties in the efforts towards systematic evaluation and draw lessons for the future.

However, this has long been a challenging endeavour, as insurgency imposes specific limitations on the data that could speak to these interactions: quantitative data is limited by the difficulties of systematic collection in war, while qualitative data may include vague or conflicting insights from direct observers.

Despite these difficulties, there has been an increasing interest in systematic large-scale mining of SARs from bioactivity data available in the public domain [33, 34].