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Missing personal details of specimen at the reference laboratory creates difficulties in specimen tracing".
Results from pathological studies are limited and hampered by technological difficulties in specimen extraction from thoracic surgery [ 4, 5].
Difficulties in specimen preparation and mounting and lack of interspinous and supraspinous ligaments [ 26] in some spines resulted in decreased sample sizes (Table 1).
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These included unwillingness of patients to provide specimens for diagnosis confirmation, lack of transport and staff for bringing samples to the reference laboratories, limited capacity in laboratories for blood/stool storage, poor quality of specimens, and difficulties in tracing specimens at reference laboratories.
CD4 count and viral suppression rates at 6 monthly intervals are shown in figure 2. countsunts were more likely to be missing than viral loads due to intermittent difficulties in transporting specimens to the laboratory (CD4 counts need to be processed more rapidly than viral loads after venepuncture).
The diagnosis of childhood TB is challenged by the paucibacillary nature of the disease and the difficulties in obtaining specimens.
Furthermore, in most cases, difficulties in interpreting histological specimen are attributable to scattering of tumor cells and small amount of tissue specimens obtained by stereotactic biopsy.
This underlines the difficulties in standardizing clinical specimens and the microbiological procedures.
Studies from the United Kingdom also reported a low cure rate owing to difficulties in obtaining sputum specimens during the last month of the treatment [ 11, 28].
Other factors that reportedly contributed to this limited utilization include the length of time needed to obtain laboratory results, and difficulties in obtaining appropriate specimens for culture, which corresponds with our findings [ 22, 30].
Transparency is of great interest to a multitude of researchers (e.g. [ 62]) but new insights are hindered by the technical difficulties in acquiring fresh specimens for most species.
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