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Subsequent studies had difficulties in replicating those findings [ 29, 30].
Such genetic drift often leads to difficulties in replicating results of mtDNA association studies among populations.
There is inconsistent use of terminology, which contributes to difficulties in replicating and understanding the association between intervention and outcomes [ 10, 11].
Like gene expression studies, proteomic studies have also been conducted using relatively small sample sizes, and there have been difficulties in replicating results.
Thus, the absence of association in other populations suggests a genetic heterogeneity in the susceptibility of schizophrenia and demonstrates the difficulties in replicating genome-wide association study findings regarding schizophrenia across different ethnic populations.
These data suggest that genetic background may play a pivotal role in effects of MF exposure; this which might explain the difficulties in replicating the original animal studies of breast tumor promotion.
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Replication of this finding with larger samples is needed, given the difficulty in replicating factor structures that were found with a small sample size.
Given the predictability of the Productivity Commission's conclusions on topics like this, private firms would have no difficulty in replicating them.
Elgar's moustache played an important role: the difficulty in replicating each strand of hair in his moustache was one of the security measures used to combat forgery when the design was introduced in 1999.
A limitation of current evidence is the difficulty in replicating the clinical situation and in determining the point at which a tissue assault becomes irreversible and results in tissue breakdown.
These manual tests can be tedious and time-consuming and have many limitations such as the inability to document the test results and the difficulty in replicating field conditions.
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