They may manifest as difficulties in establishing new research studies, or as difficulties in recruiting to established studies, therefore potentially reducing both power and generalisability.
There are, therefore, many difficulties in establishing criteria for health in terms of absolute values.
More recently, economists working on the privatization of transitional economies have focused on the difficulties in establishing viable securities markets.
Tennis has had well-documented difficulties in establishing and maintaining an African-American presence in its championship pipeline.
Argentina has none of the excuses of Eastern Europe, and a lot of the same difficulties in establishing a healthy democracy without experience.
If one person is having an affair, this is likely to break down trust and lead to difficulties in establishing honesty in a relationship.
The latter is due to difficulties in establishing a fault model equivalence when the ASIC structural netlist is passed through the design automation phases of an FPGA.
Important elements include difficulties in establishing the initial diagnosis, technical procedures, and individual adaptation of drugs and/or non-drug treatments.
A report produced by Somerset council last year highlighted problems including some missed targets, IT teething problems and difficulties in establishing a level of loyalty from transferred staff, although its customer contact centre and management spending controls were praised.
Therefore, while climate change brings many difficulties in establishing a general understanding of species vulnerability, these findings emphasize how combining trait-based approaches in light of the species evolutionary history may offer new opportunities in facing conservation challenges.
The platinum anomalies reported here for eastern sites are particularly striking, given the difficulties in establishing archaeological stratigraphy and landform chronologies for the relatively uniform, undifferentiated, sandy sediments that mark the latest Quaternary sequences of the southeastern Atlantic Coastal Plain.
