However, amplification-based sequencing platforms suffer from a sharp drop in detection of differential expression below 1000 nt, likely due to their difficulties in detecting short transcripts [31], that is not observed with this data set.
Until recently, differentially expressed miRNAs were discovered using miRNA microarray technology, which is subject to certain limitations such as difficulties in detecting low abundance miRNAs and a limited dynamic range, essentially constraining the detection of subtle fold changes.
Discusses at length the difficulties in detecting acts of embezzlement, fraud, or thievery in which computers are used.
Skimming, for instance, cannot be done in rough seas and is often limited to daylight hours because of the difficulties in detecting oil at night.
In 2005, the Supreme Court of India annulled the I.M.D.T., ruling that it had created insurmountable difficulties in detecting illegal immigrants and encouraged massive illegal immigration from Bangladesh to Assam.
Thus the OBTM data involve difficulties in detecting seafloor deformation due to tectonic motions.
However, wavelets have poor directional sensitivity and have difficulties in detecting weak diagonal cracks.
It showed that most participants did not experience difficulties in detecting the approaching train even though they did not receive any warning message.
Avoiding system/component malfunctions and failures because of the difficulties in detecting, diagnosing, and mitigating hardware faults and failures in-flight with the existing technologies.
Also, as shown in Fig. 9 c, d, some documents suffer from severe degradations and even humans may have difficulties in detecting textlines without the understanding of contents.
We have shown that uncertainties vary greatly depending on the underlying topography, the thickness of the deposit and its stratigraphic position, and difficulties in detecting true stratigraphic boundaries.
