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Second, the authors did not specify their definition of survival, that is, breast specific or overall survival, thus compounding the difficulties in data interpretation.
Investigation of the effects of MeHg provides one particular example of the difficulties in data interpretation that occur repeatedly in neurobehavioral studies and threaten to undermine confidence in this methodology.
These difficulties in data interpretation are greatly compounded for the second shell where multiscattering effects and the suppression of the Fourier transform at the higher R-range require additional simplifying assumptions.
The experimental methods are sufficient, although some methodological issues might create some difficulties in data interpretation; The results would be more convincing if isogenic strains of Pseudomonas and Drosophila were used, as differences are rather small (and possibly biologically non-significant), raising the question of genetic-background influences.
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Although effect modification has important public health implications [ 74], this issue has so far received limited attention, probably because of methodological complexity and the difficulty in data interpretation.
Although testing TP-DI in late phase for product registration is possible, it increases the complexity of pivotal phase 3 trials and is thus likely to have more confounding factors that can contribute to difficulty in data interpretation.
MM helped in data interpretation.
ST assisted in data interpretation.
CR participated in data interpretation.
TK assisted in data interpretation.
MS assisted in data interpretation.
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