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The reluctance to include children in TB research studies may result from difficulties in confirming a diagnosis (due to paucibacillary disease and difficulty in obtaining specimens); such confirmation is often a prerequisite for treatment.
Practical difficulties in confirming whether an investor's shares have been voted in accordance with the investor's instructions.
The global epidemiology of Haemophilus ducreyi infections is poorly documented because of difficulties in confirming microbiological diagnoses.
As a result childhood TB is often neglected by TB control programs due to the difficulties in confirming diagnosis, over estimating the protective efficacy of BCG vaccine [ 4].
Overall, 75% of the insertion sites that failed to be confirmed had errors in the locus-specific primer design, suggesting that sequence errors or human errors were the primary causes for difficulties in confirming an insertion site.
Despite the tremendous advances in molecular diagnosis of HNPCC that have been made since the discovery of genetic clues of this disease, the genetic etiology of many clinically defined HNPCC patients remains unsolved because of technical limitations and/or difficulties in confirming the pathogenicity of identified gene alterations [ 7].
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However, the difficulty in confirming these birth-order differences is disconcerting.
"The difficulty in confirming gender and so forth is based on how the body was found and I can't go into any more specifics in relation to that," Burk said.
Researchers said fragments of spent rockets and other hurtling hardware posed a "special political danger" because of the difficulty in confirming that an operational satellite had been struck by flying debris and had not fallen victim to an intentional attack by another nation.
Conventional backcross breeding has difficulty in confirming the several resistance genes combined in breeding lines using phenotypic selection with Xoo inoculation (Rajpurohit et al.2011; Shanti et al.2010; Sundaram et al.2008).2008
Because the resolutions of a lot of X-ray structures are not high enough, the hydrogen atoms and bond type information usually cannot be identified and even the coordinates have large errors, which bring difficulty in confirming the bond types of the structures.
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difficulties in informing
difficulties in convincing
difficulties in conforming
difficulties in recognising
difficulties in ascertaining
difficulties in making
difficulties in carrying
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difficulties in achieving
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difficulties in reducing
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