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Difficulties existed in drawing a direct comparison to smoking in humans, since humans inhale tobacco directly from cigarettes.
In cases in which difficulties existed in fibroblast identification, we recurred to coloration for vimentin and smooth muscle actin.
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However, difficulties exist in incorporating built structures in viewshed computation.
Difficulties exist in translating results of these preclinical models to therapy in humans.
Difficulties exist in assessing these, largely because the evidence from many rivers remains limited and fragmentary.
Despite this, difficulties exist in the provision of quality information aimed at describing nursing work in sufficient detail.
A solution to these difficulties exists in physiological (Tsang & Vidulich, 2006) or physio-behavioural (Funke et al., 2012) measurements.
Difficulties exist in the design and execution of surgical studies, and there are many challenges and limitations that must be addressed.
Force-diameter relationships are usually quantified by laboratory tensile tests of root diameters up to a few millimetres, but difficulties exist in extrapolating values for larger root diameters.
The authors conclude that advantage should be taken of the fact that Southern and Northern colleagues often share similar values regarding research collaborations, but difficulties exist in implementation partly due to historically rooted and current inequalities.
In modeling highly flexible beams undergoing arbitrary rigid elastic deformations, difficulties exist in describing large rotations using rotational variables, including three Euler angles, two Euler angles, one principal rotation angle plus three direction cosines of the principal rotation axis, four Euler parameters, three Rodrigues parameters, and three modified Rodrigues parameters.
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