Sentence examples for difficult to refine a from inspiring English sources
The V-ATPase is a dynamic rotary enzyme that hydrolyzes ATP through a series of differing conformational states, making it difficult to refine a three-dimensional reconstruction of the enzyme to a reasonable resolution.
It is difficult to refine a target population for recruitment to the programme on the basis of results reported herein, but larger scale studies might help to identify patients who are likely to remain in the intervention and benefit from it.
It would be difficult to refine this assessment into a quantitative metric of model value, but as a screening tool it is credible to assess that three of the models did not pass the eco-plausibility test (Table 2).
(See "The Case For $80 A Barrel Oil") According to Global Insight's Ciszuk, even a large increase from the desert kingdom would not necessarily be a boon the oil would be heavy, sour crude, which is difficult to refine and is currently trading at a big discount.
While many retailers try to present product search in a visually appealing way, search can often be slow or difficult to refine.
Hassake Province produces heavy crude, which is harder to extract, more difficult to refine and sells at lower prices than lighter oils.
But the oil is difficult to refine, and the huge investment required is hampered by the government's insistence on overvaluing the bolívar.
The principal solvent was identifiable as benzene from the initial structure solution, but was extremely difficult to refine because it exhibits librational disorder (Fig. 6).
It is difficult to refine the Bre2DBM because there is always some discontinuous residual density around the DBM peptide in the electronic density difference map for the final model.
The bill was opposed by Mint Director Robert Patterson, as it would be difficult to refine the silver from melted-down pieces.
