Sentence examples for difficult to propose the from inspiring English sources

Colchicine is also used for the management of Behcet's disease and cirrhosis so is difficult to propose the unifying mechanistic explanation for the positive effect of colchicine for the diseases with such different ethiology.

Since no closely related species of the Shortwing inhabit the Western Ghats, it is difficult to propose hypotheses regarding the past distribution or original habitat of this species.

However these models require an elastic plastic constitutive law which is difficult to propose due to the presence of high cycle secondary hardening observed on 304 stainless steel.

Given this large inter-individual variability of needs, it is difficult to propose recommendations for the general public, as has been done in many countries for energy and nutrient intakes.

It is therefore difficult to propose an overview of the evolution of the URE2 enhancer in vertebrates.

However, it is more difficult to propose an explanation for the increase in synthesis of the neuroprotective proteins tested.

At the moment it is therefore difficult to propose a function for the ancestral vertebrate Mkrn protein, but results obtained for Mkrn1 suggest a link with the regulation of cell proliferation and apoptosis [ 4, 6].

For most of the regions identified above, it remained difficult to propose candidate genes explaining the observed pattern of region differentiation.

A surprising number of designers found it difficult to propose a product from the past decade and some reached several decades back before they found a design they deemed truly beautiful.

More generally and from a desired practical point of view, this made it difficult to propose standard thresholds on the distribution of PPP-values to decide whether or not a SNP is under selection, although more sophisticated approaches could have been envisioned such as clustering techniques based on mixture models.

It is difficult to propose definite guidelines for the best strategy for testing for non-proportionality.