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Deciding what matches what therefore requires judgment, which is notoriously difficult to program in advance.
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Software writers found Itanium difficult to program.
In fact, the graph had been programmed in advance to favour either Reagan or Mondale.
Availability of this type of funding is sometimes difficult to predict in advance.
These almost endless possibilities make it difficult to craft in advance and follow a particular strategy.
But it's difficult to predict in advance which tweaks will produce the best enzymes.
Glitches are a newer phenomenon, which are difficult to predict in advance.
As a result, the potential sentence is much more difficult to determine in advance.
Since it is difficult to predict in advance which theoretical assumption is more valid, we leave this to the data.
It's very difficult to know in advance whether it's strong enough to justify a merger.
It is difficult to predict in advance".
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