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Doubly polished thin sections are much more difficult to prepare than ordinary thin sections, and therefore the polish preparation is crucial for the quality of the image.
This enabled the preparation of extended PNA sequences which are difficult to prepare by standard solid-phase methods.
Was this mix product difficult to prepare?
"It makes them very difficult to prepare for," Kill said.
"He's very difficult to prepare for and defend," Jones said.
Children from poorer backgrounds find it difficult to prepare for the information age.
"That is why it's so difficult to prepare for the match against Arsenal.
This kind of war made it difficult to prepare accurate casualty lists.
The result, though, is a team that is difficult to prepare for.
"It's going to be very difficult to prepare for Real Madrid because Wigan are in the way".
But without knowing a site is a target beforehand, it is difficult to prepare for an attack.
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