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Hence, TRPV1 is now desensitized, or more difficult to open.
Why make it difficult to open and close?
Perhaps that's why it was difficult to open.
The door was iced over, making it difficult to open.
The codex has been so tightly rebacked that it is difficult to open.
Brazil's bureaucracy even makes it difficult to open and even close a business.
Once your account is closed it's extremely difficult to open an account at another bank.
And why do they make soda cans so difficult to open these days?
A few months before, it was difficult to open the front door.
"It's difficult to open new gas stations, due to strict environmental rules," he said.
"It was very difficult to open the door again, " said Mr. Romaniello, 46.
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