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However, with the competency network example, even if nodes are contracted, it is difficult to include a negotiation 'initiation point' directly in the visualisation clicking on a node will expand or contract it, to help the user to focus on the whole or specific areas, and so this cannot also be used to initiate negotiation.
Furthermore, in a clinical geriatric setting it is difficult to include a much larger number of patients due to conditions related to the high vulnerability of these patients.
It is ethically difficult to include a true placebo arm in clinical trials of ≥6 months duration for early active RA, particularly when MTX is recommended as first-line therapy to achieve clinical remission/low disease activity.
Cohorts in large companies or public authorities are of special interest, as it would be difficult to include a large number of small factories or companies for the study.
Furthermore, in the COI method, it is difficult to consider the quality of life of the patients, and it is also difficult to include a change of utility and efficiency of a specific treatment into analysis.
Our overall impression was that the same factors that prevented nurses from participating in the survey naturally also prevented them from participating in interviews and informal talks during the qualitative assessment, making it difficult to include a substantial number of nurses representing a wider section of the staff.
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In the energy sector the uncertainty of future direction of changes in prices makes it difficult to include an adequate price vector in the design.
However, it may be difficult to include all relevant variables in a formal model.
It is difficult to include all of these candidate combinations in a single statistical model.
This makes it difficult to include all of the details surrounding the imputation procedure.
The approach emphasizes the importance of knowing the observer-connected shock source time history, which is difficult to include in a SEP event model without a realistic underlying model of the heliospheric event.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com