Sentence examples for difficult to guide from inspiring English sources

Childress and Jackson acknowledged that it would be difficult to guide the football with the injury.

However, it has been notoriously difficult to guide PSCs to differentiate into a pure population of a given cell-type.

However, classical metabolic engineering rarely considers gene regulation, and it is thus difficult to guide the selection of target genes for modification.

Despite greater methodological rigour in determining studies to include in the present systematic review, it remains difficult to guide clinicians in this vital area and most of the work discussed contained small sample sizes.

PBL can be frustrating for tutors who find it difficult to guide discussion.

Cachectic subjects are difficult to guide through chemotherapy experiencing more severe side effects resulting in progressive cachexia.

A distinction between facts and inferences may often be difficult to draw, but the guiding principle for this Court should be that when a question is in doubt and demeanor and credibility of witnesses, or contemporaneous understandings of the parties, have a part to play in its resolution, this Court should be extremely slow to upset a state court's inferential findings.

"Any community that does not make it clear what they are doing, why they are doing it, and who is welcome to join the conversation is at risk of finding it difficult to help guide the conversation later," said Lisa Stone, who created the guidelines and the BlogHer network in 2006 with Elisa Camahort and Jory Des Jardins.

It is a number-times-price calculation - the number can vary and obviously the price can vary quite materially based on who you are purchasing so it is difficult for us to guide on that".

Ultrasound has been successfully used in simulated models and difficult clinical cases to guide the tracheal puncture [ 19, 20].

Although the differences in the mean responses by treatment were statistically significant, the actual magnitude of the differences was quite small and would be difficult to use to guide clinical decisions.