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It did not take Arthur long to discover that it is difficult to formulate a useful model in conventional mathematical terms.
It is difficult to formulate a distinct definition for each of these terms, because their use largely overlaps in the literature despite individual preferences.
However, the retrospective nature of most of the studies and the small sample sizes make it difficult to formulate a clinically useful prediction rules regarding allogeneic RBC transfusion.
Despite the appropriateness of NoSQL and NewSQL data stores as cloud data management systems, the immense number of existing solutions (over 120 [10]) and the discrepancies among them make it difficult to formulate a perspective on the domain and even more challenging to select the appropriate solution for a problem at hand.
These initial biological results suggested that subtle structural changes to the phenyl and acetamide bond of C-pseudonucleosides could have a significant effect on T cell proliferation bias, although it was difficult to formulate a rigorous structure-activity relationship based on the observed activities.
The richness in our crows' behaviour makes it difficult to formulate a single model for the cognitive operations involved in sequential tool use by this (and possibly other) species.
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However, for structures without plans or insufficient structural details available it is difficult to formulate an analytical solution, especially for concrete structures where internal reinforcement details are needed to determine section capacity.
The existing assessment tools for the life cycle carbon dioxide (LCCO2) have certain limitations in that users have to directly enter quantities of materials after the construction document phase and they are likely to find it difficult to formulate an optimal strategy to reduce CO2 emissions.
It has proven difficult to formulate an unequivocal definition of the different interneuron types that exist in the brain [4].
As the program has not been tested on effectiveness before, it is difficult to formulate an effect size.
It is therefore difficult to formulate any precise hypothesis for explaining positive selection in NORK.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com