We found no differences in follow-up rates according to race/ethnicity, SES or other factors which might reasonably be used to define 'hard-to-reach' or 'difficult to find' populations -- again in contrast to the findings of several prior studies reporting difficulties retaining minority, low income, residentially unstable, or otherwise distressed individuals.
Excess deaths occur in the most deprived areas of Glasgow only, but these are precisely those groups for whom it is most difficult to find comparable populations [ 15– 17].
However, the change in the amount of unexplained difference demonstrates that it can be difficult to find compatible populations at extreme levels of deprivation.
Given that S0102 excluded HER-2 overexpressing disease and accrued patients with relatively low prior anthracycline exposure and no prior taxane, it is difficult to find trials with similar populations for comparison.
It would be difficult to find another at-risk population whose needs have been so widely ignored.
The expected breast cancer incidence in absence of screening, or background incidence, is difficult to approximate, as the introduction of a screening program makes it difficult to find an unscreened, comparable population group.
In that spirit, we would like to conclude by quoting from the commentary provided by the Spanish drug user organisations: It would be difficult to find another at-risk population whose needs have been so widely ignored….
We found that infochemicals mainly had a net positive effect on population size and population persistence in situations where resources are scarce or difficult to find or when the (local) population of fruit flies is small.
Although we separately made a stratified analysis for association of serum PL ratio with BC risk and dose response trend, it is difficult to find firm evidences among study populations within subgroup analysis, particular among USA females (P for metaregression = 0.103; P for a permutation test = 0.100).
Conversely, this variant is difficult to find in the general control population, despite the screening of large numbers of controls, even though family studies following detection of an index case disclose frequent transmissions from non-penetrant carrier parents [ 54, 57].
However, it is actually very difficult to find the accurate parameters for a population from small samples, and it is better to regard them as unknown parameters.
