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However historic distributions can be difficult to estimate objectively because substantial habitat changes may have occurred prior to comprehensive surveys.
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Therefore, it is difficult to estimate and objectively quantify the probability of detecting cases through passive surveillance, and to be able to evaluate the contribution of this SSC to the whole surveillance system's performance.
At present, no tools exist to estimate objectively the risk of poor treatment outcomes in patients with first-episode psychosis.
The long-term risks are enormous and difficult to estimate.
The actual resolution is difficult to estimate.
However, it is difficult to estimate [32].
Total population numbers are difficult to estimate.
Further, it was difficult to estimate the costs.
While "be a better person" is an admirable ambition, it's difficult to objectively judge your success at the end of the year.
As a journalist, it is difficult to write objectively about the slaughter of journalists.
Symptom burden is difficult to quantify objectively.
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