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Boivin-Roumestan says it is difficult to establish exactly how many children are affected.
"For ethical reasons you can only carry out this research on dead birds – so it's difficult to establish exactly how they've died," says Thompson.
It can be frustratingly difficult to establish exactly what the EU's money is spent on in any one year, especially if it is more recent.
But even here it remains difficult to establish exactly what it is that the observer has learned by watching the demonstrator, and more elaborate experiments may be required to elucidate this.
After the shooting in the lobby, the attackers went up in the lifts, damaging the CCTV cameras as they went, making it difficult to establish exactly where they were in the hotel, the spokesman said.
It is very difficult to establish exactly the minimal necessary dose for any given examination [1].
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Further work is needed to establish exactly how this mechanism functions.
Two further families of argument will then be considered that attempt to establish exactly that point.
Isa Umar Gusau, an adviser to Borno state's governor, told BBC Hausa: "It is very difficult to establish the number of casualties exactly.
They lack bones and scales which makes it more difficult to establish their age and determine exactly how long they live.
Exactly what happened that morning has been difficult to establish, not least because the family say they were provided with five different and often conflicting versions of events by the police in the hours that followed the death.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com