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While it is difficult to decide an appropriate recall period and most studies have used a two week recall period, we feel that weekly surveillance represents the best trade-off between missing due to recall and development of fatigue due to repeated visits [ 36, 37].
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However, it is difficult to decide a threshold correlation value above which one would classify a sample as definitively displaying the Core MYC signature.
Traumatic brain injury produces a complex pattern of diffuse axonal injury at variable locations across individuals and so it is difficult to decide a priori where to 'look' for the white matter disruption.
However, dealing with poorly differentiated tumours, it may be difficult to decide whether a tumour exhibits an NE character.
It is difficult to decide whether an image has two or more parts that are reflections of each other unless the location and orientation of the symmetry axis is specified; while one cannot determine the symmetric axis location unless two parts of the image are recognized as reflections of each other.
For the remaining referrals with no diagnostic code, it was difficult to decide whether an admission had been avoided.
For instance, it was sometimes difficult to decide whether an explanation for number of focus groups had been given and what this explanation was.
There are many variations given in the literature as to the lowest Br concentration ensuring flame retardancy in polymers and it is difficult to decide on an exact concentration.
However, it is difficult to decide whether an anchor is required at all and if so, which anchor may be the most suitable ("gold standard") for the assessment of responsiveness (transition question, disease-specific, or generic anchor).
Because tics are naturally waxing and waning, it is often difficult to decide if a worsening of tics is provoked by a drug.
For instance, it was difficult to decide if a FEB value of -8.10 kcal/mol is a Good or Regular FEB since the difference to the next FEB value was -0.10 kcal/mol only.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com