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However, it is difficult to decide a threshold correlation value above which one would classify a sample as definitively displaying the Core MYC signature.
Traumatic brain injury produces a complex pattern of diffuse axonal injury at variable locations across individuals and so it is difficult to decide a priori where to 'look' for the white matter disruption.
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While it is difficult to decide an appropriate recall period and most studies have used a two week recall period, we feel that weekly surveillance represents the best trade-off between missing due to recall and development of fatigue due to repeated visits [ 36, 37].
However, dealing with poorly differentiated tumours, it may be difficult to decide whether a tumour exhibits an NE character.
Because tics are naturally waxing and waning, it is often difficult to decide if a worsening of tics is provoked by a drug.
For instance, it was difficult to decide if a FEB value of -8.10 kcal/mol is a Good or Regular FEB since the difference to the next FEB value was -0.10 kcal/mol only.
Currently, it is very difficult to decide if a CFTR mutation is disease-causing or rather a neutral variant and if a specific gene is modifying the CF phenotype or not.
Because it can be difficult to determine whether a response immediately following exposure represents irritation-induced effects or response elicitation in a previously sensitized individual, it may be difficult to decide whether a particular reaction represents sensitization or irritation.
For 35%% of the study population it is difficult to decide if a second opinion from another physician is necessary to make an appropriate health decision (Q11).> We could calculate the HL score in 1,033 subjects.
Mr Redmond said: "It was incredibly difficult to decide on a shortlist as all the bids recognised the power of culture to bring about social change and offered innovative and interesting programmes.
However, the broad range of usability inspection and testing methods available may make it difficult to decide on a usability assessment plan.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com