Sentence examples for difficult to crystallize and from inspiring English sources
Three of the mutant dimers crystallized readily (in four to seven days) in contrast to the wild-type protein, which is particularly difficult to crystallize and takes more than a month to form diffraction-quality crystals.
Naked RNAs are difficult to crystallize and NMR spectroscopy is generally limited to small RNA fragments.
Beyond four icosahedral units, however, it becomes increasingly difficult to crystallize and chararacterize the compound.
Membrane proteins, by contrast, are difficult to crystallize and are underrepresented in the PDB.
Unfortunately, GPCRs are notoriously difficult to crystallize and so far only five independent GPCR X-ray structures have been determined.
For example, membrane enzymes are very difficult to crystallize and most of them will not dissolve in normal solvents.
Besides, part of the as-deposited La2O3 film close to the IL could be considered as Si-riched and difficult to crystallize as Si rich help to prevent the formation of crystalline La2O3 precipitates [29].
Practicing chemists soon learn, often simply by experience, that it is frequently very difficult to crystallize a newly synthesized substance, while subsequent crystallizations are considerably more facile.
Novel tools and technologies are required to obtain structural information of difficult to crystallize complex biological systems such as membrane proteins, multiprotein assemblies, transient conformational states and intrinsically disordered proteins.
