Sentence examples for difficult to construct the from inspiring English sources

It will be difficult to construct the high school.

This makes it difficult to construct the computational algorithms.

It is difficult to construct the reduced-order burn-up chain because it requires engineers to have highly skilled techniques and in-depth knowledge into burn-up processes.

Because the conformational change of aptamer upon its target or probe/target/probe sandwich often is the primary prerequisite for the design of an electrochemical aptameric assay system, it is extremely difficult to construct the electrochemical aptasensor for protein assay because the corresponding aptamers cannot often meet the requirement.

In some cases, for metabolic transformations catalysed by cytochromes P450, it is difficult to construct the structures of the metabolites based only on knowledge of the SOMs.

Second, the theory of Mawhin's continuation theorem is characterized by the higher dimension of kernel space on resonance BVPs, the more difficult to construct the projections P and Q.

The auditor's report, commissioned in 2006, complimented the tram as "a dramatic, one-of-a-kind facility that will become a Portland landmark," and noted that the design was difficult to construct, requiring the tall, thin, complex tower and the tall, heavily loaded upper terminal to be built within very tight tolerances.

According to Harries et al. (2005), the first confinement option is practically difficult to construct when the average shear stress in the beam is greater than ( 0.5sqrt {f'_{c} } ) MPa, where f' c is the concrete compressive strength in MPa.

2a) Fully complementing fluorescent fusions of MreB (both wild-type and point-mutants) have proven difficult to construct in the lab, suggesting that many single amino-acid perturbations, be it at the interface or not, can be enough to disrupt proper MreB function.

The fact that similarity networks are not based on a single multiple sequence alignment is an important advantage: a good multiple sequence alignment can be very difficult to construct in the case of a large or diverse sequence set.

However, both ZFNs and TALENs are nuclease-based designs that are difficult to construct, and the efficiency of targeting varies substantially, making these laborious approaches.